[16] EPILEPSY: BRIDGING TRADITIONAL UNDERSTANDING AND CONTEMPORARY CLINICAL PRACTICE

ARTICLE INFO: Date of Submission: May 20, 2025, Revised: June 17, 2025, Accepted: June 23, 2025, https://doi.org/10.56815/ijmrr.v4i2.2025.201-220

Abstract

Epilepsy is a long-term neurological condition marked by repeated seizures that occur without any clear trigger, caused by irregular electrical impulses in the brain. Despite significant advances in neuroscience, the global burden of epilepsy remains high, particularly in low- and middle-income countries. This review seeks to present an in-depth understanding of epilepsy by combining age-old perspectives with current clinical knowledge and practices. It highlights historical perspectives on epilepsy, cultural beliefs, and ancient therapeutic approaches, while aligning them with current understanding of its etiology, classification, diagnostic criteria, and treatment modalities. Emphasis is placed on contemporary pharmacological therapies, surgical options, and emerging interventions such as neuromodulation and dietary therapies. In addition, the role of traditional and complementary medicine—including the use of herbal formulations and mind-body practices—is critically evaluated for their potential as adjuncts to conventional care. This integrative approach underscores the importance of a multidisciplinary perspective in improving patient outcomes, enhancing treatment adherence, and reducing stigma associated with epilepsy. The review concludes by identifying gaps in current practice and suggesting future research directions to bridge cultural beliefs with evidence-based medicine.